DSG4抗体应用：WB 1:500-2000 ELISA 1:5000-20000desmoglein 4(DSG4) Homo sapiens This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016],

DTL抗体应用：WB 1:500-2000 ELISA 1:5000-20000developmental stage:Expressed in all fetal tissues examined, included brain, lung, liver, and kidney.,function:Required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase. Seems to be necessary to ensure proper cell cycle regulation of DNA replication. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. May play a role in cell proliferation of NT2 embryonal carcinoma cells.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the WD repeat cdt2 family.,similarity:Contains 7 WD repeats.,subcellular location:Nuclear matrix-associated protein. Translocates from the interphase nucleus to the metaphase cytoplasm during mitosis.,subunit:Probable part of a cullin-RING E3 protein ligase complex containing CUL4B-DDB1 and a substrate-recruiting component (DCAF). Interacts with CUL4B and DDB1.,tissue specificity:Expressed in placenta and testis, ve

DTWD1抗体应用：WB 1:500-2000

DUPD1抗体应用：WB 1:500-2000

DUS14抗体应用：WB 1:500-2000 ELISA 1:5000-20000dual specificity phosphatase 14(DUSP14) Homo sapiens Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009],

DUS15抗体应用：WB 1:500-2000The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

DUS1L抗体应用：WB 1:500-2000

DUS26抗体应用：WB 1:500-2000 ELISA 1:5000-20000dual specificity phosphatase 26 (putative)(DUSP26) Homo sapiens This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

DUX4抗体应用：WB 1:500-2000

DUX5抗体应用：WB 1:500-2000 ELISA 1:5000-20000double homeobox 5(DUX5) Homo sapiens The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008],