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ING3 rabbit Polyclonal Antibody

ING3抗体
ING3抗体应用:WB 1:500-2000 ELISA 1:5000-20000inhibitor of growth family member 3(ING3) Homo sapiens The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008],

ING5 rabbit Polyclonal Antibody

ING5抗体
ING5抗体应用:WB 1:500-2000 ELISA 1:5000-20000inhibitor of growth family member 5(ING5) Homo sapiens This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016],

INGR2 rabbit Polyclonal Antibody

INGR2抗体
INGR2抗体应用:WB 1:500-2000 ELISA 1:5000-20000interferon gamma receptor 2 (interferon gamma transducer 1)(IFNGR2) Homo sapiens This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008],

INP5E rabbit Polyclonal Antibody

INP5E抗体
INP5E抗体应用:WB 1:500-2000 ELISA 1:5000-20000

INSI2 rabbit Polyclonal Antibody

INSI2抗体
INSI2抗体应用:WB 1:500-2000 ELISA 1:5000-20000insulin induced gene 2(INSIG2) Homo sapiens The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008],

INSL5 rabbit Polyclonal Antibody

INSL5抗体
INSL5抗体应用:WB 1:500-2000 ELISA 1:5000-20000insulin like 5(INSL5) Homo sapiens The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). [provided by RefSeq, Jul 2008],

IPO9 rabbit Polyclonal Antibody

IPO9抗体
IPO9抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May al

HXC11 rabbit Polyclonal Antibody

HXC11抗体
HXC11抗体应用:WB 1:500-2000 ELISA 1:5000-20000homeobox C11(HOXC11) Homo sapiens This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008],

HXC12 rabbit Polyclonal Antibody

HXC12抗体
HXC12抗体应用:WB 1:500-2000 ELISA 1:5000-20000homeobox C12(HOXC12) Homo sapiens This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. [provided by RefSeq, Jul 2008],

HXC13 rabbit Polyclonal Antibody

HXC13抗体
HXC13抗体应用:WB 1:500-2000 ELISA 1:5000-20000homeobox C13(HOXC13) Homo sapiens This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla. [provided by RefSeq, Jul 2008],
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