PAR2抗体应用：WB 1:500-2000 ELISA 1:5000-20000F2R like trypsin receptor 1(F2RL1) Homo sapiens This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016],

PAR6G抗体应用：WB 1:500-2000 ELISA 1:5000-20000domain:The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,function:Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,similarity:Belongs to the PAR6 family.,similarity:Contains 1 OPR domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,

PARG抗体应用：WB 1:500-2000 This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],

PARP6抗体应用：WB 1:500-2000 ELISA 1:5000-20000catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,similarity:Contains 1 PARP catalytic domain.,

PARP8抗体应用：WB 1:500-2000 ELISA 1:5000-20000catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 PARP catalytic domain.,

PARP9抗体应用：WB 1:500-2000 ELISA 1:5000-20000catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,miscellaneous:Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 2 Macro domains.,subunit:Interacts with BBAP.,tissue specificity:Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form.,

PARPT抗体应用：WB 1:500-2000 ELISA 1:5000-20000TCDD inducible poly(ADP-ribose) polymerase(TIPARP) Homo sapiens This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

PARVA抗体应用：WB 1:500-2000 ELISA 1:5000-20000This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010],

PASD1抗体应用：WB 1:500-2000This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010],

PASK抗体应用：WB 1:500-2000 ELISA 1:5000-20000PAS domain containing serine/threonine kinase(PASK) Homo sapiens This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],