产品中心

IL-17D rabbit Polyclonal Antibody

IL-17D抗体
IL-17D抗体应用:IHC-p 1:50-200, ELISA 1:10000-20000 interleukin 17D(IL17D) Homo sapiens The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008],

IL-17F rabbit Polyclonal Antibody

IL-17F抗体
IL-17F抗体应用:IHC-p 1:50-200, ELISA 1:10000-20000 interleukin 17F(IL17F) Homo sapiens The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008],

IL-17RB rabbit Polyclonal Antibody

IL-17RB抗体
IL-17RB抗体应用:WB 1:500-2000, ELISA 1:10000-20000 interleukin 17 receptor B(IL17RB) Homo sapiens The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008],

IL-17RC rabbit Polyclonal Antibody

IL-17RC抗体
IL-17RC抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000.interleukin 17 receptor C(IL17RC) Homo sapiens This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011],

IL-17Rα rabbit Polyclonal Antibody

IL-17Rα抗体
IL-17Rα抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. interleukin 17 receptor A(IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

IL-17Rα rabbit Polyclonal Antibody

IL-17Rα抗体
IL-17Rα抗体应用:IHC-p 1:50-200, WB 1:500-2000 interleukin 17 receptor A(IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

IL-18R rabbit Polyclonal Antibody

IL-18R抗体
IL-18R抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. interleukin 18 receptor 1(IL18R1) Homo sapiens The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],

IL-18R rabbit Polyclonal Antibody

IL-18R抗体
IL-18R抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. interleukin 18 receptor 1(IL18R1) Homo sapiens The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],

IL-19 rabbit Polyclonal Antibody

IL-19 抗体
IL-19 抗体应用:WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 interleukin 19(IL19) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],

IL-1F10 rabbit Polyclonal Antibody

IL-1F10抗体
IL-1F10抗体应用:Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. interleukin 1 family member 10 (theta)(IL1F10) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],
沪ICP备15039594号-4
在线客服
专业的客服团队,欢迎在线资讯
客服时间: 周一至周五9:00 - 18:00