FACR1 rabbit polyclonal antibody
应用:WB 1:500-2000
产品名:FACR1 rabbit Polyclonal Antibody
货号:ATA29035
种类(Category)
Primary antibodies
宿主(Host)
Rabbit
反应种属(Species specificity)
Human, Mouse,Rat
应用实验(Tested applications)
WB
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
免疫原(Immunogen)
Synthesized peptide derived from human FACR1
状态(Form)
Liquid
存放条件(Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.
纯化方式(Purity)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
产品背景:The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015],
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!