PREP rabbit polyclonal antibody
应用:WB 1:500-2000 ELISA 1:5000-20000
产品名:PREP rabbit Polyclonal Antibody
货号:ATA35881
种类(Category)
Primary antibodies
宿主(Host)
Rabbit
反应种属(Species specificity)
Human,Mouse
应用实验(Tested applications)
WB,ELISA
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
免疫原(Immunogen)
Synthesized peptide derived from human protein . at AA range: 450-530
状态(Form)
Liquid
存放条件(Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.
纯化方式(Purity)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
产品背景:cofactor:Binds 1 zinc ion per subunit.,function:ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.,PTM:The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions, suggesting that it may participate in redox regulation of the enzyme.,similarity:Belongs to the peptidase M16 family. PreP subfamily.,subunit:Homodimer.,tissue specificity:Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.,
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!