IL-12B rabbit polyclonal antibody
应用:WB 1:500-2000, ELISA(peptide)1:5000-20000
产品名:IL-12B rabbit Polyclonal Antibody
货号:ATA31367
种类(Category)
Primary antibodies
宿主(Host)
Rabbit
反应种属(Species specificity)
Human
应用实验(Tested applications)
WB, ELISA
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
免疫原(Immunogen)
Synthesized peptide derived from human IL-12B
状态(Form)
Liquid
存放条件(Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.
纯化方式(Purity)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
产品背景:interleukin 12B(IL12B) Homo sapiens This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provi
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