ERI1 rabbit polyclonal antibody
应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000.
产品名:ERI1 rabbit Polyclonal Antibody
货号:ATA28822
种类(Category)
Primary antibodies
宿主(Host)
Rabbit
反应种属(Species specificity)
Human,Mouse,Rat
应用实验(Tested applications)
WB,ELISA
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
免疫原(Immunogen)
The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310
状态(Form)
Liquid
存放条件(Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.
纯化方式(Purity)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
产品背景:cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity.,function:RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Required for 5.8S rRNA 3'-end processing.,sequence caution:Translated as Leu.,similarity:Contains 1 exonuclease domain.,similarity:Contains 1 SAP domain.,subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5.8s ribosomal RNA.,
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