WNT4 rabbit polyclonal antibody
应用:WB 1:500-2000 ELISA 1:5000-20000
产品名:WNT4 rabbit Polyclonal Antibody
货号:ATA39669
种类(Category)
Primary antibodies
宿主(Host)
Rabbit
反应种属(Species specificity)
Human,Mouse,Rat
应用实验(Tested applications)
WB,ELISA
克隆性(Clonality)
Polyclonal
偶连物(Conjugation)
Unconjugated
免疫原(Immunogen)
Synthesized peptide derived from human protein . at AA range: 190-270
状态(Form)
Liquid
存放条件(Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.
纯化方式(Purity)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
产品背景:Wnt family member 4(WNT4) Homo sapiens The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSe
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