多克隆抗体

FGF21 rabbit Polyclonal Antibody

FGF21抗体
FGF21抗体应用:WB 1:500-2000 ELISA 1:5000-20000fibroblast growth factor 21(FGF21) Homo sapiens Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016],

FGF3 rabbit Polyclonal Antibody

FGF3抗体
FGF3抗体应用:WB 1:500-2000 ELISA 1:5000-20000fibroblast growth factor 3(FGF3) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008],

FGFP1 rabbit Polyclonal Antibody

FGFP1抗体
FGFP1抗体应用:WB 1:500-2000 ELISA 1:5000-20000fibroblast growth factor binding protein 1(FGFBP1) Homo sapiens This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011],

FGFP3 rabbit Polyclonal Antibody

FGFP3抗体
FGFP3抗体应用:WB 1:500-2000 ELISA 1:5000-20000similarity:Belongs to the fibroblast growth factor-binding protein family.,subunit:Interacts with FGF1.,

FGFR1 rabbit Polyclonal Antibody

FGFR1抗体
FGFR1抗体应用:WB 1:500-2000 ELISA 1:5000-20000fibroblast growth factor receptor 1(FGFR1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,

FGGY rabbit Polyclonal Antibody

FGGY抗体
FGGY抗体应用:WB 1:500-2000 ELISA 1:5000-20000FGGY carbohydrate kinase domain containing(FGGY) Homo sapiens This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

FHL2 rabbit Polyclonal Antibody

FHL2抗体
FHL2抗体应用:WB 1:500-2000 ELISA 1:5000-20000four and a half LIM domains 2(FHL2) Homo sapiens This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016],

FHL3 rabbit Polyclonal Antibody

FHL3抗体
FHL3抗体应用:WB 1:500-2000 ELISA 1:5000-20000four and a half LIM domains 3(FHL3) Homo sapiens The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

FHR1 rabbit Polyclonal Antibody

FHR1抗体
FHR1抗体应用:WB 1:500-2000 ELISA 1:5000-20000complement factor H related 1(CFHR1) Homo sapiens This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009],

FHR5 rabbit Polyclonal Antibody

FHR5抗体
FHR5抗体应用:WB 1:500-2000This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],
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