HCAR1抗体应用：WB 1:500-2000 ELISA 1:5000-20000hydroxycarboxylic acid receptor 1(HCAR1) Homo sapiens G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Feb 2005],

HCAR2抗体应用：WB 1:500-2000 ELISA 1:5000-20000developmental stage:Expression in neutrophils occurs in the late terminal differentiation phase.,function:Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.,miscellaneous:The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotin

HCN1抗体应用：WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 1(HCN1) Homo sapiens The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011],

HCN3抗体应用：WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 3(HCN3) Homo sapiens This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

HEY1抗体应用：WB 1:500-2000 ELISA 1:5000-20000hes related family bHLH transcription factor with YRPW motif 1(HEY1) Homo sapiens This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],

HCN4抗体应用：WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 4(HCN4) Homo sapiens This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008],

HCP5抗体应用：WB 1:500-2000

HEAT1抗体应用：WB 1:500-2000 ELISA 1:5000-20000function:Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the HEATR1/UTP10 family.,similarity:Contains 1 HEAT repeat.,

HECAM抗体应用：WB 1:500-2000 ELISA 1:5000-20000hepatic and glial cell adhesion molecule(HEPACAM) Homo sapiens The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011],

HECD1抗体应用：IHC-p 1:50-300function:Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the UPL family. K-HECT subfamily.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 MIB/HERC2 domain.,similarity:Contains 4 ANK repeats.,