多克隆抗体

PGM1 rabbit Polyclonal Antibody

PGM1抗体
PGM1抗体应用:WB 1:500-2000The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010],

PGM5 rabbit Polyclonal Antibody

PGM5抗体
PGM5抗体应用:WB 1:500-2000Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008],

PGRC1 rabbit Polyclonal Antibody

PGRC1抗体
PGRC1抗体应用:WB 1:500-2000 ELISA 1:5000-20000progesterone receptor membrane component 1(PGRMC1) Homo sapiens This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010],

PGRP3 rabbit Polyclonal Antibody

PGRP3抗体
PGRP3抗体应用:WB 1:500-2000 ELISA 1:5000-20000peptidoglycan recognition protein 3(PGLYRP3) Homo sapiens This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],

PGRP4 rabbit Polyclonal Antibody

PGRP4抗体
PGRP4抗体应用:WB 1:500-2000 ELISA 1:5000-20000peptidoglycan recognition protein 4(PGLYRP4) Homo sapiens Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],

PGS1 rabbit Polyclonal Antibody

PGS1抗体
PGS1抗体应用:WB 1:500-2000 ELISA 1:5000-20000biglycan(BGN) Homo sapiens This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015],

PGS2 rabbit Polyclonal Antibody

PGS2抗体
PGS2抗体应用:WB 1:500-2000 ELISA 1:5000-20000decorin(DCN) Homo sapiens This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015],

PGTA rabbit Polyclonal Antibody

PGTA抗体
PGTA抗体应用:WB 1:500-2000

PHB2 rabbit Polyclonal Antibody

PHB2抗体
PHB2抗体应用:WB 1:500-2000 ELISA 1:5000-20000developmental stage:Levels of expression in fibroblasts decrease heterogeneously during cellular aging.,function:Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.,induction:Expression increases approximately 3-fold upon entry into G1 phase compared to other phases of the cell cycle. Also induced following inhibition of mitochondrial protein synthesis by thiamphenicol.,similarity:Belongs to the prohibitin family.,subcellular location:Also cytoplasmic and nuclear.,subunit:Interacts with PHB, ESR1, HDAC1 and HDAC5.,

PHC3 rabbit Polyclonal Antibody

PHC3抗体
PHC3抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FCS-type zinc finger.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2.,
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