多克隆抗体

PTH2R rabbit Polyclonal Antibody

PTH2R抗体
PTH2R抗体应用:WB 1:500-2000 ELISA 1:5000-20000parathyroid hormone 2 receptor(PTH2R) Homo sapiens The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

PTHD2 rabbit Polyclonal Antibody

PTHD2抗体
PTHD2抗体应用:WB 1:500-2000 ELISA 1:5000-20000developmental stage:Expressed in fetal brain.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,tissue specificity:Expressed in brain and testis.,

PTHD3 rabbit Polyclonal Antibody

PTHD3抗体
PTHD3抗体应用:WB 1:500-2000

PTMA rabbit Polyclonal Antibody

PTMA抗体
PTMA抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.,PTM:Covalently linked to a small RNA of about 20 nucleotides.,similarity:Belongs to the pro/parathymosin family.,

PTN12 rabbit Polyclonal Antibody

PTN12抗体
PTN12抗体应用:WB 1:500-2000 ELISA 1:5000-20000protein tyrosine phosphatase, non-receptor type 12(PTPN12) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoform

PTN13 rabbit Polyclonal Antibody

PTN13抗体
PTN13抗体应用:IHC-p 1:50-300protein tyrosine phosphatase, non-receptor type 13(PTPN13) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha

PTN14 rabbit Polyclonal Antibody

PTN14抗体
PTN14抗体应用:WB 1:500-2000 ELISA 1:5000-20000protein tyrosine phosphatase, non-receptor type 14(PTPN14) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010],

PTN18 rabbit Polyclonal Antibody

PTN18抗体
PTN18抗体应用:WB 1:500-2000 ELISA 1:5000-20000protein tyrosine phosphatase, non-receptor type 18(PTPN18) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008],

PTN2 rabbit Polyclonal Antibody

PTN2抗体
PTN2抗体应用:WB 1:500-2000 ELISA 1:5000-20000protein tyrosine phosphatase, non-receptor type 2(PTPN2) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011],

PTN21 rabbit Polyclonal Antibody

PTN21抗体
PTN21抗体应用:WB 1:500-2000 ELISA 1:5000-20000protein tyrosine phosphatase, non-receptor type 21(PTPN21) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008],
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