多克隆抗体

RANG rabbit Polyclonal Antibody

RANG抗体
RANG抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAN binding protein 1(RANBP1) Homo sapiens This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

RAP1A rabbit Polyclonal Antibody

RAP1A抗体
RAP1A抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAP1A, member of RAS oncogene family(RAP1A) Homo sapiens This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

RAP1B rabbit Polyclonal Antibody

RAP1B抗体
RAP1B抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAP1B, member of RAS oncogene family(RAP1B) Homo sapiens This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011],

RAPH1 rabbit Polyclonal Antibody

RAPH1抗体
RAPH1抗体应用:WB 1:500-2000 ELISA 1:5000-20000Ras association (RalGDS/AF-6) and pleckstrin homology domains 1(RAPH1) Homo sapiens This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],

RARA rabbit Polyclonal Antibody

RARA抗体
RARA抗体应用:WB 1:500-2000 ELISA 1:5000-20000retinoic acid receptor alpha(RARA) Homo sapiens This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010],

RARG rabbit Polyclonal Antibody

RARG抗体
RARG抗体应用:WB 1:500-2000 ELISA 1:5000-20000retinoic acid receptor gamma(RARG) Homo sapiens This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

RARR2 rabbit Polyclonal Antibody

RARR2抗体
RARR2抗体应用:WB 1:500-2000 ELISA 1:5000-20000retinoic acid receptor responder 2(RARRES2) Homo sapiens This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi. [provided by RefSeq, Nov 2014],

RASA1 rabbit Polyclonal Antibody

RASA1抗体
RASA1抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAS p21 protein activator 1(RASA1) Homo sapiens The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expres

RASA2 rabbit Polyclonal Antibody

RASA2抗体
RASA2抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAS p21 protein activator 2(RASA2) Homo sapiens The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

RASEF rabbit Polyclonal Antibody

RASEF抗体
RASEF抗体应用:WB 1:500-2000 ELISA 1:5000-20000RAS and EF-hand domain containing(RASEF) Homo sapiens This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012],
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