SETBP抗体应用：WB 1:500-2000This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

SF3A1抗体应用：WB 1:500-2000 ELISA 1:5000-20000splicing factor 3a subunit 1(SF3A1) Homo sapiens This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014],

SF3A3抗体应用：WB 1:500-2000 ELISA 1:5000-20000splicing factor 3a subunit 3(SF3A3) Homo sapiens This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

SF3B5抗体应用：IHC-p 1：50-200

SFPQ抗体应用：WB 1:500-2000 ELISA 1:5000-20000alternative products:Additional isoforms seem to exist,caution:Was originally (PubMed:2480877) thought to be myoblast cell surface antigen 24.1D5 and a possible membrane-bound protein ectokinase.,disease:A chromosomal aberration involving SFPQ may be a cause of papillary renal cell carcinoma (PRCC). Translocation t(X;1)(p11.2;p34) with TFE3.,function:DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer associated with MATR3

SFR1抗体应用：WB 1:500-2000

SFRP1抗体应用：WB 1:500-2000 ELISA 1:5000-20000secreted frizzled related protein 1(SFRP1) Homo sapiens This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009],

SFRP3抗体应用：WB 1:500-2000 ELISA 1:5000-20000frizzled-related protein(FRZB) Homo sapiens The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. [provided by RefSeq, Apr 2010],

SFRP4抗体应用：WB 1:500-2000 ELISA 1:5000-20000secreted frizzled related protein 4(SFRP4) Homo sapiens Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008],

SFT2A抗体应用：WB 1:500-2000 ELISA 1:5000-20000function:May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.,similarity:Belongs to the SFT2 family.,