CaMKIIα/β/δ rabbit Polyclonal Antibody
CaMKIIα/β/δ抗体
CaMKIIα/β/δ抗体应用:WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. calcium/calmodulin dependent protein kinase II alpha(CAMK2A) Homo sapiens The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],