CD249抗体应用：Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.,

CD26抗体应用：Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. dipeptidyl peptidase 4(DPP4) Homo sapiens The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. [provided by RefSeq, Jul 2008],

CD264抗体应用：Western Blot: 1/500 - 1/2000. ELISA: 1/10000. TNF receptor superfamily member 10d(TNFRSF10D) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008],

CD267抗体应用：Western Blot: 1/500 - 1/2000. ELISA: 1/10000. TNF receptor superfamily member 13B(TNFRSF13B) Homo sapiens The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008],

CD269抗体应用：Western Blot: 1/500 - 1/2000. ELISA: 1/10000.TNF receptor superfamily member 17(TNFRSF17) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008],

CD272抗体应用：IHC-p 1:50-200, ELISA 1:10000-20000 B and T lymphocyte associated(BTLA) Homo sapiens This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],

CD272抗体应用：Western Blot: 1/500 - 1/2000. ELISA: 1/40000. B and T lymphocyte associated(BTLA) Homo sapiens This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],

CD274抗体应用：IHC-p 1:50-200, ELISA 1:10000-20000 CD274 molecule(CD274) Homo sapiens This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

CD275抗体应用：IHC-p 1:50-200, ELISA 1:10000-20000 alternative products:Additional isoforms seem to exist,function:Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.,induction:Constitutive expression is further enhanced by treatment with TNF-alpha in peripheral blood B-cells and monocytes, while it is decreased in dendritic cells.,sequence caution:The sequence differs from that shown in position 300 onward for unknown reason.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-t

CD276抗体应用：Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. CD276 molecule(CD276) Homo sapiens The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],