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HCN1 rabbit Polyclonal Antibody

HCN1抗体
HCN1抗体应用:WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 1(HCN1) Homo sapiens The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011],

HCN3 rabbit Polyclonal Antibody

HCN3抗体
HCN3抗体应用:WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 3(HCN3) Homo sapiens This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

HEY1 rabbit Polyclonal Antibody

HEY1抗体
HEY1抗体应用:WB 1:500-2000 ELISA 1:5000-20000hes related family bHLH transcription factor with YRPW motif 1(HEY1) Homo sapiens This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],

HCN4 rabbit Polyclonal Antibody

HCN4抗体
HCN4抗体应用:WB 1:500-2000 ELISA 1:5000-20000hyperpolarization activated cyclic nucleotide gated potassium channel 4(HCN4) Homo sapiens This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008],

HCP5 rabbit Polyclonal Antibody

HCP5抗体
HCP5抗体应用:WB 1:500-2000

HEAT1 rabbit Polyclonal Antibody

HEAT1抗体
HEAT1抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the HEATR1/UTP10 family.,similarity:Contains 1 HEAT repeat.,

HECAM rabbit Polyclonal Antibody

HECAM抗体
HECAM抗体应用:WB 1:500-2000 ELISA 1:5000-20000hepatic and glial cell adhesion molecule(HEPACAM) Homo sapiens The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011],

HECD1 rabbit Polyclonal Antibody

HECD1抗体
HECD1抗体应用:IHC-p 1:50-300function:Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the UPL family. K-HECT subfamily.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 MIB/HERC2 domain.,similarity:Contains 4 ANK repeats.,

HECW1 rabbit Polyclonal Antibody

HECW1抗体
HECW1抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.,tissue specificity:Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.,

HEM1 rabbit Polyclonal Antibody

HEM1抗体
HEM1抗体应用:WB 1:500-2000 This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
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