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MCEM1 rabbit Polyclonal Antibody

MCEM1抗体
MCEM1抗体应用:WB 1:500-2000 ELISA 1:5000-20000mast cell expressed membrane protein 1(MCEMP1) Homo sapiens This gene encodes a single-pass transmembrane protein. Based on its expression pattern, it is speculated to be involved in regulating mast cell differentiation or immune responses. [provided by RefSeq, Jul 2008],

MCF2 rabbit Polyclonal Antibody

MCF2抗体
MCF2抗体应用:WB 1:500-2000 ELISA 1:5000-20000MCF.2 cell line derived transforming sequence(MCF2) Homo sapiens The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010],

MCF2L rabbit Polyclonal Antibody

MCF2L抗体
MCF2L抗体应用:WB 1:500-2000 ELISA 1:5000-20000MCF.2 cell line derived transforming sequence like(MCF2L) Homo sapiens This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

MCHR1 rabbit Polyclonal Antibody

MCHR1抗体
MCHR1抗体应用:WB 1:500-2000 ELISA 1:5000-20000melanin concentrating hormone receptor 1(MCHR1) Homo sapiens The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008],

MCLN2 rabbit Polyclonal Antibody

MCLN2抗体
MCLN2抗体应用:WB 1:500-2000 Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009],

MCM8 rabbit Polyclonal Antibody

MCM8抗体
MCM8抗体应用:WB 1:500-2000 ELISA 1:5000-20000minichromosome maintenance 8 homologous recombination repair factor(MCM8) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013],

MCM9 rabbit Polyclonal Antibody

MCM9抗体
MCM9抗体应用:WB 1:500-2000 ELISA 1:5000-20000minichromosome maintenance 9 homologous recombination repair factor(MCM9) Homo sapiens The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010],

MCP rabbit Polyclonal Antibody

MCP抗体
MCP抗体应用:WB 1:500-2000 ELISA 1:5000-20000CD46 molecule(CD46) Homo sapiens The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010],

MCR rabbit Polyclonal Antibody

MCR抗体
MCR抗体应用:WB 1:500-2000 ELISA 1:5000-20000nuclear receptor subfamily 3 group C member 2(NR3C2) Homo sapiens This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

MDFIC rabbit Polyclonal Antibody

MDFIC抗体
MDFIC抗体应用:WB 1:500-2000 ELISA 1:5000-20000MyoD family inhibitor domain containing(MDFIC) Homo sapiens This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
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