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TBCB rabbit Polyclonal Antibody

TBCB抗体
TBCB抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.,PTM:Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.,similarity:Belongs to the TBCB family.,similarity:Contains 1 CAP-Gly domain.,subcellular location:Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.,subunit:Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interac

TBD rabbit Polyclonal Antibody

TBD抗体
TBD抗体应用:WB 1:500-2000 ELISA 1:5000-20000alternative products:Experimental confirmation may be lacking for some isoforms,function:In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.,similarity:Belongs to the tubulin family.,subcellular location:Associated with centrioles. Both cytoplasmic and nuclear.,

TBD2A rabbit Polyclonal Antibody

TBD2A抗体
TBD2A抗体应用:WB 1:500-2000 ELISA 1:5000-20000function:May act as a GTPase-activating protein for Rab family protein(s).,similarity:Contains 1 PH domain.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Expressed in a broad range of tissues. Differentially expressed in prostate normal and cancer cells.,

TBD2B rabbit Polyclonal Antibody

TBD2B抗体
TBD2B抗体应用:WB 1:500-2000

TBG1 rabbit Polyclonal Antibody

TBG1抗体
TBG1抗体应用:WB 1:500-2000 ELISA 1:5000-20000tubulin gamma 1(TUBG1) Homo sapiens This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],

TBG2 rabbit Polyclonal Antibody

TBG2抗体
TBG2抗体应用:WB 1:500-2000

TBR1 rabbit Polyclonal Antibody

TBR1抗体
TBR1抗体应用:WB 1:500-2000 ELISA 1:5000-20000T-box, brain 1(TBR1) Homo sapiens This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015],

TBX15 rabbit Polyclonal Antibody

TBX15抗体
TBX15抗体应用:WB 1:500-2000 ELISA 1:5000-20000T-box 15(TBX15) Homo sapiens This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009],

TBX20 rabbit Polyclonal Antibody

TBX20抗体
TBX20抗体应用:WB 1:500-2000 ELISA 1:5000-20000T-box 20(TBX20) Homo sapiens This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

TBX21 rabbit Polyclonal Antibody

TBX21抗体
TBX21抗体应用:WB 1:500-2000 ELISA 1:5000-20000T-box 21(TBX21) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008],
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