MTSS1抗体应用：WB 1:500-2000 ELISA 1:5000-20000domain:The WH2 motif at the C-terminus binds to actin monomers.,function:May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.,similarity:Belongs to the MTSS1 family.,similarity:Contains 1 IMD (IRSp53/MIM homology) domain.,similarity:Contains 1 WH2 domain.,subunit:Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta.,tissue specificity:Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.,

MTU1抗体应用：WB 1:500-2000 ELISA 1:5000-20000This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

MUC15抗体应用：WB 1:500-2000 ELISA 1:5000-20000function:May play a role in the cell adhesion to the extracellular matrix.,PTM:Highly glycosylated (N- and O-linked carbohydrates).,sequence caution:Translated as stop.,tissue specificity:Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, bone marrow, lymph node and lung.,

MUC21抗体应用：WB 1:500-2000

MUC22抗体应用：WB 1:500-2000

MUC3A抗体应用：IHC-p 1:50-300

MUC4抗体应用：WB 1:500-2000 ELISA 1:5000-20000mucin 4, cell surface associated(MUC4) Homo sapiens The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008],

MUC5A抗体应用：IHC-p 1:50-300domain:The cysteine residues in the Cys-rich subdomain repeats are not involved in disulfide bonding.,function:Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particules that are subsequently removed by the mucocilary system.,PTM:C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis.,PTM:Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 2 VWFC

MUC5B抗体应用：IHC-p 1:50-300mucin 5B, oligomeric mucus/gel-forming(MUC5B) Homo sapiens This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010],

MUC7抗体应用：WB 1:500-2000 ELISA 1:5000-20000mucin 7, secreted(MUC7) Homo sapiens This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Oct 2014],