抗体

PARP8 rabbit Polyclonal Antibody

PARP8抗体
PARP8抗体应用:WB 1:500-2000 ELISA 1:5000-20000catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 PARP catalytic domain.,

PARP9 rabbit Polyclonal Antibody

PARP9抗体
PARP9抗体应用:WB 1:500-2000 ELISA 1:5000-20000catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,miscellaneous:Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 2 Macro domains.,subunit:Interacts with BBAP.,tissue specificity:Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form.,

PARPT rabbit Polyclonal Antibody

PARPT抗体
PARPT抗体应用:WB 1:500-2000 ELISA 1:5000-20000TCDD inducible poly(ADP-ribose) polymerase(TIPARP) Homo sapiens This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

PARVA rabbit Polyclonal Antibody

PARVA抗体
PARVA抗体应用:WB 1:500-2000 ELISA 1:5000-20000This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010],

PASD1 rabbit Polyclonal Antibody

PASD1抗体
PASD1抗体应用:WB 1:500-2000This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010],

PASK rabbit Polyclonal Antibody

PASK抗体
PASK抗体应用:WB 1:500-2000 ELISA 1:5000-20000PAS domain containing serine/threonine kinase(PASK) Homo sapiens This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

PATL1 rabbit Polyclonal Antibody

PATL1抗体
PATL1抗体应用:WB 1:500-2000 ELISA 1:5000-20000

PAX3 rabbit Polyclonal Antibody

PAX3抗体
PAX3抗体应用:WB 1:500-2000 ELISA 1:5000-20000paired box 3(PAX3) Homo sapiens This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008],

PAX7 rabbit Polyclonal Antibody

PAX7抗体
PAX7抗体应用:WB 1:500-2000 ELISA 1:5000-20000paired box 7(PAX7) Homo sapiens This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],

PBIP1 rabbit Polyclonal Antibody

PBIP1抗体
PBIP1抗体应用:WB 1:500-2000 The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015],
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