抗体

RND2 rabbit Polyclonal Antibody

RND2抗体
RND2抗体应用:WB 1:500-2000 ELISA 1:5000-20000Rho family GTPase 2(RND2) Homo sapiens This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008],

RND3 rabbit Polyclonal Antibody

RND3抗体
RND3抗体应用:WB 1:500-2000 ELISA 1:5000-20000Rho family GTPase 3(RND3) Homo sapiens This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],

RNF37 rabbit Polyclonal Antibody

RNF37抗体
RNF37抗体应用:WB 1:500-2000 This gene encodes a U-box domain containing protein. The encoded protein interacts with E2 enzymes and may play a role in the ubiquitination pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],

RNF41 rabbit Polyclonal Antibody

RNF41抗体
RNF41抗体应用:WB 1:500-2000 ELISA 1:5000-20000ring finger protein 41(RNF41) Homo sapiens This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

RNF5 rabbit Polyclonal Antibody

RNF5抗体
RNF5抗体应用:WB 1:500-2000 ELISA 1:5000-20000ring finger protein 5(RNF5) Homo sapiens The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. [provided by RefSeq, Jul 2008],

RNF6 rabbit Polyclonal Antibody

RNF6抗体
RNF6抗体应用:WB 1:500-2000 ELISA 1:5000-20000ring finger protein 6(RNF6) Homo sapiens The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008],

RO52 rabbit Polyclonal Antibody

RO52抗体
RO52抗体应用:WB 1:500-2000 ELISA 1:5000-20000tripartite motif containing 21(TRIM21) Homo sapiens This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],

ROA0 rabbit Polyclonal Antibody

ROA0抗体
ROA0抗体应用:WB 1:500-2000 ELISA 1:5000-20000heterogeneous nuclear ribonucleoprotein A0(HNRNPA0) Homo sapiens This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. [provided by RefSeq, Jul 2008],

ROAA rabbit Polyclonal Antibody

ROAA抗体
ROAA抗体应用:WB 1:500-2000 ELISA 1:5000-20000heterogeneous nuclear ribonucleoprotein A/B(HNRNPAB) Homo sapiens This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

ROBO1 rabbit Polyclonal Antibody

ROBO1抗体
ROBO1抗体应用:WB 1:500-2000 ELISA 1:5000-20000roundabout guidance receptor 1(ROBO1) Homo sapiens Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
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