抗体

ABCG2 rabbit Polyclonal Antibody

ABCG2抗体
ABCG2抗体应用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Mu

ABHD11 rabbit Polyclonal Antibody

ABHD11抗体
ABHD11抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.abhydrolase domain containing 11(ABHD11) Homo sapiens This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016],

ABHD12 rabbit Polyclonal Antibody

ABHD12抗体
ABHD12抗体应用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.abhydrolase domain containing 12(ABHD12) Homo sapiens This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],

ABHD12B rabbit Polyclonal Antibody

ABHD12B抗体
ABHD12B抗体应用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.similarity:Belongs to the serine esterase family.,

ABHD14A rabbit Polyclonal Antibody

ABHD14A抗体
ABHD14A抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.caution:It is uncertain whether Met-1 or Met-30 is the initiator.,function:Possible role in granule neuron development.,similarity:Belongs to the AB hydrolase superfamily. ABHD14 family.,

ABHD14B rabbit Polyclonal Antibody

ABHD14B抗体
ABHD14B抗体应用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.function:Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription.,similarity:Belongs to the AB hydrolase superfamily. ABHD14 family.,subcellular location:Predominantly cytoplasmic.,subunit:May interact with TAF1.,tissue specificity:Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney.,

ABHD2 rabbit Polyclonal Antibody

ABHD2抗体
ABHD2抗体应用:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.abhydrolase domain containing 2(ABHD2) Homo sapiens This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

ABHD4 rabbit Polyclonal Antibody

ABHD4抗体
ABHD4抗体应用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,

ABHD6 rabbit Polyclonal Antibody

ABHD6抗体
ABHD6抗体应用:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.catalytic activity:Hydrolyzes glycerol monoesters of long-chain fatty acids.,function:Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways.,similarity:Belongs to the AB hydrolase superfamily.,

ABHD7 rabbit Polyclonal Antibody

ABHD7抗体
ABHD7抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD7 is a 362 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and
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