抗体

FRP-2 rabbit Polyclonal Antibody

FRP-2抗体
FRP-2抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. secreted frizzled related protein 2(SFRP2) Homo sapiens This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008],

FRS2 rabbit Polyclonal Antibody

FRS2抗体
FRS2抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence caution:Translated as stop.,similarity:Contains 1 IRS-type PTB domain.,subcellular location:Cytoplasmic, membrane-bound.,subunit:Part of a complex containing FRS2, GRB2 and SOS1. Part of a complex containing GRB2 and CBL. Binds RET (By similarity). Binds FGFR1, SUC1, NTRK1, NTRK2, NTRK3 and SRC. The tyrosine-phosphorylated protein binds the SH2 domains of GRB2 and PTPN11.,tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.,

FRS2 rabbit Polyclonal Antibody

FRS2抗体
FRS2抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence caution:Translated as stop.,similarity:Contains 1 IRS-type PTB domain.,subcellular location:Cytoplasmic, membrane-bound.,subunit:Part of a complex containing FRS2, GRB2 and SOS1. Part of a complex containing GRB2 and CBL. Binds RET (By similarity). Binds FGFR1, SUC1, NTRK1, NTRK2, NTRK3 and SRC. The tyrosine-phosphorylated protein binds the SH2 domains of GRB2 and PTPN11.,tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.,

FRS3 rabbit Polyclonal Antibody

FRS3抗体
FRS3抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. fibroblast growth factor receptor substrate 3(FRS3) Homo sapiens This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013],

FR-α rabbit Polyclonal Antibody

FR-α抗体
FR-α抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. folate receptor 1(FOLR1) Homo sapiens The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009],

FSD1L rabbit Polyclonal Antibody

FSD1L抗体
FSD1L抗体应用:WB 1:500-2000

FSHR rabbit Polyclonal Antibody

FSHR抗体
FSHR抗体应用:IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. follicle stimulating hormone receptor(FSHR) Homo sapiens The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],

FSHR rabbit Polyclonal Antibody

FSHR抗体
FSHR抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. follicle stimulating hormone receptor(FSHR) Homo sapiens The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],

FSHβ rabbit Polyclonal Antibody

FSHβ抗体
FSHβ抗体应用:IHC-p 1:50-200, ELISA 1:10000-20000 follicle stimulating hormone beta subunit(FSHB) Homo sapiens The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

FTO rabbit Polyclonal Antibody

FTO抗体
FTO抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. FTO, alpha-ketoglutarate dependent dioxygenase(FTO) Homo sapiens This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],
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