GRB7抗体应用：IHC-p 1:50-200, ELISA 1:10000-20000 growth factor receptor bound protein 7(GRB7) Homo sapiens The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],

GRCR1抗体应用：WB 1:500-2000 This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010],

Gremlin-2抗体应用：WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 gremlin 2, DAN family BMP antagonist(GREM2) Homo sapiens This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],

GRF-1抗体应用：Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000.Rho GTPase activating protein 35(ARHGAP35) Homo sapiens The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008],

GRHPR抗体应用：WB 1:500-2000 This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008],

GRIF-1抗体应用：Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. PTM:O-glycosylated.,similarity:Contains 1 HAP1 N-terminal domain.,subunit:Interacts with GABA-A receptor and O-GlcNAc transferase (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.,tissue specificity:Widely expressed, with highest expression in heart.,

GRIK3抗体应用：WB 1:500-2000 Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008],

GRIN1抗体应用：Western Blot: 1/500 - 1/2000. ELISA: 1/40000. function:May be involved in neurite outgrowth.,PTM:Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting.,subcellular location:Highly enriched in growth cone.,subunit:Interacts with activated forms of GNAI1, GNAO1 and GNAZ.,tissue specificity:Widely expressed in the central nervous system, with highest levels in spinal cord.,

GRIN1抗体应用：WB 1:500-2000, ELISA 1:10000-20000 glutamate ionotropic receptor NMDA type subunit 1(GRIN1) Homo sapiens The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

GRIN2抗体应用：Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. function:May be involved in neurite outgrowth.,subunit:Interacts with activated forms of GNAO1 and GNAZ.,tissue specificity:Expressed specifically in the cerebellum.,