抗体

IL-17Rα rabbit Polyclonal Antibody

IL-17Rα抗体
IL-17Rα抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. interleukin 17 receptor A(IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

IL-17Rα rabbit Polyclonal Antibody

IL-17Rα抗体
IL-17Rα抗体应用:IHC-p 1:50-200, WB 1:500-2000 interleukin 17 receptor A(IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

IL-18R rabbit Polyclonal Antibody

IL-18R抗体
IL-18R抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. interleukin 18 receptor 1(IL18R1) Homo sapiens The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],

IL-18R rabbit Polyclonal Antibody

IL-18R抗体
IL-18R抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. interleukin 18 receptor 1(IL18R1) Homo sapiens The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],

IL-19 rabbit Polyclonal Antibody

IL-19 抗体
IL-19 抗体应用:WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 interleukin 19(IL19) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],

IL-1F10 rabbit Polyclonal Antibody

IL-1F10抗体
IL-1F10抗体应用:Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. interleukin 1 family member 10 (theta)(IL1F10) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],

IL-1F5 rabbit Polyclonal Antibody

IL-1F5抗体
IL-1F5抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. interleukin 36 receptor antagonist(IL36RN) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],

IL-1F6 rabbit Polyclonal Antibody

IL-1F6抗体
IL-1F6抗体应用:IHC-p 1:50-200, ELISA 1:10000-20000 interleukin 36, alpha(IL36A) Homo sapiens The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015],

IL-1F7 rabbit Polyclonal Antibody

IL-1F7抗体
IL-1F7抗体应用:IHC-p 1:50-200, ELISA 1:10000-20000 interleukin 37(IL37) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

IL-1F8 rabbit Polyclonal Antibody

IL-1F8抗体
IL-1F8抗体应用:Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. interleukin 36, beta(IL36B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
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