抗体

EID-1 rabbit Polyclonal Antibody

EID-1抗体
EID-1抗体应用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. developmental stage:Expression decreased with development in ventricular tissue while remaining highly expressed in adult atrial tissue. In primary cultures of human skeletal myocytes, expression decreased during myogenic differentiation (at protein level).,function:Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.,induction:Down-regulated in differentiating U937 leukemia cells.,miscellaneous:Inhibition of MYOD1 may be partly due to the ability of EID1 to bind and inhibit EP300 histone acetyltransferase activity.,PTM:Ubiquitinated

eIF1AY rabbit Polyclonal Antibody

eIF1AY抗体
eIF1AY抗体应用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. eukaryotic translation initiation factor 1A, Y-linked(EIF1AY) Homo sapiens This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

eIF1B rabbit Polyclonal Antibody

eIF1B抗体
eIF1B抗体应用:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000.function:Probably involved in translation.,similarity:Belongs to the SUI1 family.,

eIF2Bγ rabbit Polyclonal Antibody

eIF2Bγ抗体
eIF2Bγ抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. eukaryotic translation initiation factor 2B subunit gamma(EIF2B3) Homo sapiens The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

eIF2Bδ rabbit Polyclonal Antibody

eIF2Bδ抗体
eIF2Bδ抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. eukaryotic translation initiation factor 2B subunit delta(EIF2B4) Homo sapiens Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

eIF2α rabbit Polyclonal Antibody

eIF2α抗体
eIF2α抗体应用:IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. eukaryotic translation initiation factor 2 subunit alpha(EIF2S1) Homo sapiens The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

eIF2β rabbit Polyclonal Antibody

eIF2β抗体
eIF2β抗体应用:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. eukaryotic translation initiation factor 2 subunit beta(EIF2S2) Homo sapiens Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

eIF2β rabbit Polyclonal Antibody

eIF2β抗体
eIF2β抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. eukaryotic translation initiation factor 2 subunit beta(EIF2S2) Homo sapiens Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

EIF3I rabbit Polyclonal Antibody

EIF3I抗体
EIF3I抗体应用:WB 1:500-2000

eIF3K rabbit Polyclonal Antibody

eIF3K抗体
eIF3K抗体应用:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. eukaryotic translation initiation factor 3 subunit K(EIF3K) Homo sapiens The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008],
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